Medellin to Santiago

1 ways to travelfastest 3h 56mfly from €374
Photo: Chalo Gallardo / Unsplash

Departure-day prices · November 2026 Medellin → Santiago

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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.

Return-day prices · November 2026 Santiago → Medellin

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Best time to visit Santiago — climate

Jan: ~27°C daytime, 11 rainy days 27° JanFeb: ~28°C daytime, 13 rainy days 28° FebMar: ~31°C daytime, 13 rainy days 31° MarApr: ~28°C daytime, 22 rainy days 28° AprMay: ~31°C daytime, 15 rainy days 31° MayJun: ~31°C daytime, 16 rainy days 31° JunJul: ~32°C daytime, 18 rainy days 32° JulAug: ~33°C daytime, 20 rainy days 33° AugSep: ~32°C daytime, 21 rainy days 32° SepOct: ~31°C daytime, 20 rainy days 31° OctNov: ~30°C daytime, 9 rainy days 30° NovDec: ~29°C daytime, 9 rainy days 29° Dec

Flights from Medellin to Santiago start around €374 (typically 1 stop). Range seen recently: €374–374, based on 1 fares found by travellers.

Fly (from €374)
3h 56mduration
€374–374recent fares
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Cheapest cached fares Medellin → Santiago; typically 1 stop (e.g. CM). · Based on 1 fares found by travellers in the last 48h

Weather in Santiago

Sat 🌦️ 32° 23° 💧96%
Sun 🌦️ 31° 22° 💧98%
Mon 🌦️ 32° 22° 💧80%
Tue 🌦️ 32° 22° 💧78%
Wed ☁️ 32° 23° 💧73%
Thu ⛈️ 31° 23° 💧96%
Fri ⛈️ 31° 23° 💧100%

In Nov, Santiago typically sees ~30°C daytime highs and 9 rainy days.

Good to know

Time difference+1h

Things to do in Santiago

Top-rated tours and tickets from €25 — book ahead for the popular ones.

Tours and tickets provided by Viator (a Tripadvisor company). Some links earn Stayonomy a commission.

About Santiago

Santiago is the capital and economic center of Chile. With its many museums, events, theaters, restaurants, bars and other entertainment and cultural opportunities, it is also the cultural center of the country. For visitors it's both the gateway to the country and a destination in its own right with an eclectic architecture, a vibrant culinary and cultural scene, surrounded by the mighty Andes welcoming skiers, trekkers and friends of wine.

Read the full Santiago guide

Guide content from Wikivoyage contributors (CC BY-SA).

Round out the trip

Popular from Medellin

Cheapest destinations travellers searched recently — refreshed daily.

Flight prices are real fares travellers found in the last 48 hours, refreshed daily — the booking site confirms the final price. Train, bus and ferry fares are shown on the operators' booking sites. Weather data by Open-Meteo; exchange rates: ECB reference. Data updated 2026-10-10. Some links earn Stayonomy a commission at no cost to you.