Departure-day prices · September 2026 Panama City → Comayagua
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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.
Return-day prices · September 2026 Comayagua → Panama City
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Best time to visit Comayagua — climate Jan: ~28°C daytime, 12 rainy days
28°
Jan Feb: ~31°C daytime, 12 rainy days
31°
Feb Mar: ~33°C daytime, 6 rainy days
33°
Mar Apr: ~32°C daytime, 10 rainy days
32°
Apr May: ~35°C daytime, 11 rainy days
35°
May Jun: ~30°C daytime, 26 rainy days
30°
Jun Jul: ~32°C daytime, 19 rainy days
32°
Jul Aug: ~32°C daytime, 23 rainy days
32°
Aug Sep: ~31°C daytime, 24 rainy days
31°
Sep Oct: ~29°C daytime, 28 rainy days
29°
Oct Nov: ~28°C daytime, 12 rainy days
28°
Nov Dec: ~28°C daytime, 19 rainy days
28°
Dec Flights from Panama City to Comayagua start around €264 (direct flights available). Range seen recently: €264–264, based on 1 fares found by travellers.
Fly (from €264)
2h 00m duration
€264–264 recent fares
Book
Cheapest cached fares Panama City → Comayagua; direct flights available (e.g. CM). · Based on 1 fares found by travellers in the last 48h
Cheapest round trips to Comayagua Fares found by travellers in the last 48 hours — refreshed daily.
Sep 23 – Oct 15
Copa Airlines · Direct · 2h 00m
€290
Book
Sep 28 – Oct 15
avianca airlines · 1 stop · 2h 50m
€294
Book
Weather in Comayagua
Sun
🌦️
36°
23°
💧24%
Mon
🌦️
34°
22°
💧84%
Tue
🌦️
36°
23°
💧58%
Wed
🌦️
35°
22°
💧67%
Thu
🌦️
34°
21°
💧72%
Fri
☁️
34°
22°
💧45%
Sat
🌦️
34°
22°
💧91%
In Sep, Comayagua typically sees ~31°C daytime highs and 24 rainy days.
Where to stay in Comayagua 3★+ hotels from €49/night (3 hotels sampled, ~3 weeks out).
Hotel Antigua Comayagua
hotel · Comayagua
from €49/night ★ 3
Hotel Caxa Real
hotel · Comayagua
from €75/night ★ 3
Tru By Hilton Distrito Palmerola
hotel · Comayagua
from €89/night ★ 4
Good to know Time difference -1h
Time in the air 2h 00m
About Comayagua
Comayagua is a historical city in and once brief capital of Honduras. It has maintained much of its picturesque Spanish Colonial era architecture.
Read the full Comayagua guide
Guide content from Wikivoyage contributors (CC BY-SA).
Popular from Panama City Cheapest destinations travellers searched recently — refreshed daily.
Flight prices are real fares travellers found in the last 48 hours, refreshed daily — the booking site confirms the final price. Train, bus and ferry fares are shown on the operators' booking sites. Weather data by Open-Meteo ; exchange rates: ECB reference. Data updated 2026-09-06. Some links earn Stayonomy a commission at no cost to you.