Panama City to Comayagua

1 ways to travelfastest 2h 00mfly from €264

Departure-day prices · September 2026 Panama City → Comayagua

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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.

Return-day prices · September 2026 Comayagua → Panama City

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Best time to visit Comayagua — climate

Jan: ~28°C daytime, 12 rainy days 28° JanFeb: ~31°C daytime, 12 rainy days 31° FebMar: ~33°C daytime, 6 rainy days 33° MarApr: ~32°C daytime, 10 rainy days 32° AprMay: ~35°C daytime, 11 rainy days 35° MayJun: ~30°C daytime, 26 rainy days 30° JunJul: ~32°C daytime, 19 rainy days 32° JulAug: ~32°C daytime, 23 rainy days 32° AugSep: ~31°C daytime, 24 rainy days 31° SepOct: ~29°C daytime, 28 rainy days 29° OctNov: ~28°C daytime, 12 rainy days 28° NovDec: ~28°C daytime, 19 rainy days 28° Dec

Flights from Panama City to Comayagua start around €264 (direct flights available). Range seen recently: €264–264, based on 1 fares found by travellers.

Fly (from €264)
2h 00mduration
€264–264recent fares
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Cheapest cached fares Panama City → Comayagua; direct flights available (e.g. CM). · Based on 1 fares found by travellers in the last 48h

Cheapest round trips to Comayagua

Fares found by travellers in the last 48 hours — refreshed daily.

Sep 23 – Oct 15 Copa Airlines · Direct · 2h 00m €290 Book
Sep 28 – Oct 15 avianca airlines · 1 stop · 2h 50m €294 Book

Weather in Comayagua

Sun 🌦️ 36° 23° 💧24%
Mon 🌦️ 34° 22° 💧84%
Tue 🌦️ 36° 23° 💧58%
Wed 🌦️ 35° 22° 💧67%
Thu 🌦️ 34° 21° 💧72%
Fri ☁️ 34° 22° 💧45%
Sat 🌦️ 34° 22° 💧91%

In Sep, Comayagua typically sees ~31°C daytime highs and 24 rainy days.

Where to stay in Comayagua

3★+ hotels from €49/night (3 hotels sampled, ~3 weeks out).

Hotel Antigua Comayagua hotel · Comayagua
from €49/night★ 3
Hotel Caxa Real hotel · Comayagua
from €75/night★ 3
Tru By Hilton Distrito Palmerola hotel · Comayagua
from €89/night★ 4

Good to know

Time difference-1h
Time in the air2h 00m

About Comayagua

Comayagua is a historical city in and once brief capital of Honduras. It has maintained much of its picturesque Spanish Colonial era architecture.

Read the full Comayagua guide

Guide content from Wikivoyage contributors (CC BY-SA).

Round out the trip

Popular from Panama City

Cheapest destinations travellers searched recently — refreshed daily.

Flight prices are real fares travellers found in the last 48 hours, refreshed daily — the booking site confirms the final price. Train, bus and ferry fares are shown on the operators' booking sites. Weather data by Open-Meteo; exchange rates: ECB reference. Data updated 2026-09-06. Some links earn Stayonomy a commission at no cost to you.