Panama City to Mexico City

1 ways to travelfastest 3h 49mfly from €177
Photo: Bhargava Marripati / Unsplash

How the cheapest fare moved

Nov 13: €181 €181 Nov 8 Nov 13 low €177 · high €326

Departure-day prices · November 2026 Panama City → Mexico City

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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.

Return-day prices · November 2026 Mexico City → Panama City

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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.

Best time to visit Mexico City — climate

Jan: ~23°C daytime, 2 rainy days 23° JanFeb: ~24°C daytime, 4 rainy days 24° FebMar: ~28°C daytime, 4 rainy days 28° MarApr: ~29°C daytime, 0 rainy days 29° AprMay: ~27°C daytime, 16 rainy days 27° MayJun: ~23°C daytime, 24 rainy days 23° JunJul: ~23°C daytime, 23 rainy days 23° JulAug: ~23°C daytime, 29 rainy days 23° AugSep: ~23°C daytime, 30 rainy days 23° SepOct: ~23°C daytime, 11 rainy days 23° OctNov: ~23°C daytime, 2 rainy days 23° NovDec: ~21°C daytime, 5 rainy days 21° Dec

Best value: Dec — fares from €177 and ~21°C daytime.

Flights from Panama City to Mexico City start around €177 (direct flights available). Range seen recently: €177–266, based on 8 fares found by travellers.

Fly (from €177)
3h 49mduration
€177–266recent fares
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Cheapest cached fares Panama City → Mexico City; direct flights available (e.g. AM). · Based on 8 fares found by travellers in the last 48h

Cheapest round trips to Mexico City

Fares found by travellers in the last 48 hours — refreshed daily.

Dec 22 – Jan 6 Aeromexico · Direct · 3h 51m €317 Book
Dec 14 – Dec 21 Aeromexico · Direct · 3h 53m €319 Book
Dec 24 – Dec 27 Aeromexico · Direct · 3h 51m €338 Book
Feb 5 – Feb 9 Aeromexico · Direct · 3h 49m €389 Book
Nov 26 – Nov 29 Aeromexico · Direct · 3h 53m €425 Book
Jun 15 – Jun 26 Aeromexico · Direct · 4h 00m €455 Book
Nov 26 – Dec 27 Copa Airlines · Direct · 3h 44m €467 Book
Nov 29 – Dec 27 Copa Airlines · Direct · 3h 51m €467 Book

Weather in Mexico City

Fri 🌦️ 19° 10° 💧82%
Sat 🌦️ 20° 10° 💧47%
Sun 🌫️ 21° 8° 💧2%
Mon 🌦️ 21° 10° 💧51%
Tue ☁️ 21° 11° 💧34%
Wed 🌦️ 22° 10° 💧24%
Thu 🌦️ 22° 11° 💧53%

In Nov, Mexico City typically sees ~23°C daytime highs and 2 rainy days.

Where to stay in Mexico City

3★+ hotels from €64/night (39 hotels sampled, ~3 weeks out).

Hotel & Suites PF hotel · Mexico City
from €64/night★ 4
Sevilla Palace hotel · Mexico City
from €71/night★ 4
Emporio Reforma hotel · Mexico City
from €79/night★ 5

Good to know

Time difference-1h
Time in the air3h 44m

Things to do in Mexico City

Top-rated tours and tickets from €82 — book ahead for the popular ones.

Tours and tickets provided by Viator (a Tripadvisor company). Some links earn Stayonomy a commission.

About Mexico City

Mexico City (Spanish: México, Ciudad de México or CDMX) is the capital of the Mexican Republic, the most populous city in the country, and one of the most important financial and cultural centers of the American continent. The city center is built on the ruins of the Aztec capital Tenochtitlan, and later came to be the capital of New Spain, which included much of North America.

Read the full Mexico City guide

Guide content from Wikivoyage contributors (CC BY-SA).

Round out the trip

Popular from Panama City

Cheapest destinations travellers searched recently — refreshed daily.

Flight prices are real fares travellers found in the last 48 hours, refreshed daily — the booking site confirms the final price. Train, bus and ferry fares are shown on the operators' booking sites. Weather data by Open-Meteo; exchange rates: ECB reference. Data updated 2026-11-14. Some links earn Stayonomy a commission at no cost to you.