How the cheapest fare moved
Oct 24: €423
€423
Oct 17
Oct 24
low €367 · high €447
Departure-day prices · October 2026 Panama City → Santo Domingo
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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.
Return-day prices · October 2026 Santo Domingo → Panama City
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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.
Best time to visit Santo Domingo — climate Jan: ~29°C daytime, 10 rainy days
29°
Jan Feb: ~29°C daytime, 12 rainy days
29°
Feb Mar: ~29°C daytime, 19 rainy days
29°
Mar Apr: ~29°C daytime, 19 rainy days
29°
Apr May: ~30°C daytime, 21 rainy days
30°
May Jun: ~30°C daytime, 25 rainy days
30°
Jun Jul: ~31°C daytime, 28 rainy days
31°
Jul Aug: ~31°C daytime, 24 rainy days
31°
Aug Sep: ~31°C daytime, 23 rainy days
31°
Sep Oct: ~30°C daytime, 22 rainy days
30°
Oct Nov: ~29°C daytime, 15 rainy days
29°
Nov Dec: ~29°C daytime, 11 rainy days
29°
Dec Best value: Dec — fares from €367 and ~29°C daytime.
Flights from Panama City to Santo Domingo start around €367 (typically 1 stop). Range seen recently: €367–404, based on 9 fares found by travellers.
Fly (from €367)
3h 50m duration
€367–404 recent fares
Book
Cheapest cached fares Panama City → Santo Domingo; typically 1 stop (e.g. CM). · Based on 9 fares found by travellers in the last 48h
Cheapest round trips to Santo Domingo Fares found by travellers in the last 48 hours — refreshed daily.
Dec 10 – Jan 30
Copa Airlines · Direct · 2h 23m
€430
Book
Oct 28 – Nov 28
avianca airlines · 1 stop · 4h 15m
€473
Book
Jan 3 – Feb 10
Copa Airlines · Direct · 2h 24m
€496
Book
Weather in Santo Domingo
Fri
⛈️
31°
22°
💧91%
Sat
🌦️
30°
24°
💧84%
Sun
⛈️
29°
23°
💧88%
Mon
⛈️
28°
24°
💧86%
Tue
🌧️
28°
23°
💧80%
Wed
⛈️
28°
23°
💧76%
Thu
🌦️
30°
23°
💧50%
In Oct, Santo Domingo typically sees ~30°C daytime highs and 22 rainy days.
Where to stay in Santo Domingo 3★+ hotels from €33/night (33 hotels sampled, ~3 weeks out).
Ramada Santo Domingo Princess Hotel
hotel · Santo Domingo
from €33/night ★ 3
La Casona Dorada
hotel · Santo Domingo
from €45/night ★ 3
Hotel Riazor
hotel · Santo Domingo
from €61/night ★ 3
Good to know Time difference +1h
Time in the air 2h 23m
Things to do in Santo Domingo Top-rated tours and tickets from €41 — book ahead for the popular ones.
Tours and tickets provided by Viator (a Tripadvisor company). Some links earn Stayonomy a commission.
About Santo Domingo
Santo Domingo is the capital of the Dominican Republic, the oldest European city in the Americas, and the most developed city on the island of Hispaniola. The old city is on the UNESCO World Heritage List. Elsewhere in the Dominican Republic, which is named after Santo Domingo, it's more common to just call this city "the capital" than to call it by its name.
Read the full Santo Domingo guide
Guide content from Wikivoyage contributors (CC BY-SA).
Popular from Panama City Cheapest destinations travellers searched recently — refreshed daily.
Flight prices are real fares travellers found in the last 48 hours, refreshed daily — the booking site confirms the final price. Train, bus and ferry fares are shown on the operators' booking sites. Weather data by Open-Meteo ; exchange rates: ECB reference. Data updated 2026-10-24. Some links earn Stayonomy a commission at no cost to you.