Panama City to Santo Domingo

1 ways to travelfastest 3h 50mfly from €367
Photo: Yi Wei / Unsplash

How the cheapest fare moved

Oct 24: €423 €423 Oct 17 Oct 24 low €367 · high €447

Departure-day prices · October 2026 Panama City → Santo Domingo

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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.

Return-day prices · October 2026 Santo Domingo → Panama City

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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.

Best time to visit Santo Domingo — climate

Jan: ~29°C daytime, 10 rainy days 29° JanFeb: ~29°C daytime, 12 rainy days 29° FebMar: ~29°C daytime, 19 rainy days 29° MarApr: ~29°C daytime, 19 rainy days 29° AprMay: ~30°C daytime, 21 rainy days 30° MayJun: ~30°C daytime, 25 rainy days 30° JunJul: ~31°C daytime, 28 rainy days 31° JulAug: ~31°C daytime, 24 rainy days 31° AugSep: ~31°C daytime, 23 rainy days 31° SepOct: ~30°C daytime, 22 rainy days 30° OctNov: ~29°C daytime, 15 rainy days 29° NovDec: ~29°C daytime, 11 rainy days 29° Dec

Best value: Dec — fares from €367 and ~29°C daytime.

Flights from Panama City to Santo Domingo start around €367 (typically 1 stop). Range seen recently: €367–404, based on 9 fares found by travellers.

Fly (from €367)
3h 50mduration
€367–404recent fares
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Cheapest cached fares Panama City → Santo Domingo; typically 1 stop (e.g. CM). · Based on 9 fares found by travellers in the last 48h

Cheapest round trips to Santo Domingo

Fares found by travellers in the last 48 hours — refreshed daily.

Dec 10 – Jan 30 Copa Airlines · Direct · 2h 23m €430 Book
Oct 28 – Nov 28 avianca airlines · 1 stop · 4h 15m €473 Book
Jan 3 – Feb 10 Copa Airlines · Direct · 2h 24m €496 Book

Weather in Santo Domingo

Fri ⛈️ 31° 22° 💧91%
Sat 🌦️ 30° 24° 💧84%
Sun ⛈️ 29° 23° 💧88%
Mon ⛈️ 28° 24° 💧86%
Tue 🌧️ 28° 23° 💧80%
Wed ⛈️ 28° 23° 💧76%
Thu 🌦️ 30° 23° 💧50%

In Oct, Santo Domingo typically sees ~30°C daytime highs and 22 rainy days.

Where to stay in Santo Domingo

3★+ hotels from €33/night (33 hotels sampled, ~3 weeks out).

Ramada Santo Domingo Princess Hotel hotel · Santo Domingo
from €33/night★ 3
La Casona Dorada hotel · Santo Domingo
from €45/night★ 3
Hotel Riazor hotel · Santo Domingo
from €61/night★ 3

Good to know

Time difference+1h
Time in the air2h 23m

Things to do in Santo Domingo

Top-rated tours and tickets from €41 — book ahead for the popular ones.

Tours and tickets provided by Viator (a Tripadvisor company). Some links earn Stayonomy a commission.

About Santo Domingo

Santo Domingo is the capital of the Dominican Republic, the oldest European city in the Americas, and the most developed city on the island of Hispaniola. The old city is on the UNESCO World Heritage List. Elsewhere in the Dominican Republic, which is named after Santo Domingo, it's more common to just call this city "the capital" than to call it by its name.

Read the full Santo Domingo guide

Guide content from Wikivoyage contributors (CC BY-SA).

Round out the trip

Popular from Panama City

Cheapest destinations travellers searched recently — refreshed daily.

Flight prices are real fares travellers found in the last 48 hours, refreshed daily — the booking site confirms the final price. Train, bus and ferry fares are shown on the operators' booking sites. Weather data by Open-Meteo; exchange rates: ECB reference. Data updated 2026-10-24. Some links earn Stayonomy a commission at no cost to you.