Departure-day prices · September 2026 San Antonio → Des Moines
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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.
Return-day prices · September 2026 Des Moines → San Antonio
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Best time to visit Des Moines — climate Jan: ~-1°C daytime, 2 rainy days
-1°
Jan Feb: ~-0°C daytime, 5 rainy days
-0°
Feb Mar: ~13°C daytime, 10 rainy days
13°
Mar Apr: ~17°C daytime, 11 rainy days
17°
Apr May: ~22°C daytime, 9 rainy days
22°
May Jun: ~29°C daytime, 13 rainy days
29°
Jun Jul: ~30°C daytime, 15 rainy days
30°
Jul Aug: ~28°C daytime, 9 rainy days
28°
Aug Sep: ~26°C daytime, 8 rainy days
26°
Sep Oct: ~20°C daytime, 9 rainy days
20°
Oct Nov: ~10°C daytime, 5 rainy days
10°
Nov Dec: ~2°C daytime, 7 rainy days
2°
Dec Flights from San Antonio to Des Moines start around €248 (typically 2 stops). Range seen recently: €248–248, based on 1 fares found by travellers.
Fly (from €248)
10h 23m duration
€248–248 recent fares
Book
Cheapest cached fares San Antonio → Des Moines; typically 2 stops (e.g. F9). · Based on 1 fares found by travellers in the last 48h
Cheapest round trips to Des Moines Fares found by travellers in the last 48 hours — refreshed daily.
Sep 5 – Sep 5
United Airlines · 1 stop · 4h 32m
€279
Book
Sep 4 – Sep 4
American Airlines · 1 stop · 3h 16m
€374
Book
Weather in Des Moines
Fri
☁️
30°
15°
💧1%
Sat
☁️
34°
18°
💧21%
Sun
☁️
42°
26°
💧12%
Mon
🌦️
38°
25°
💧28%
Tue
🌦️
40°
23°
💧24%
Wed
🌦️
37°
25°
💧26%
Thu
🌤️
42°
22°
💧21%
In Sep, Des Moines typically sees ~26°C daytime highs and 8 rainy days.
Where to stay in Des Moines 3★+ hotels from €59/night (29 hotels sampled, ~3 weeks out).
Quality Inn Des Moines North
hotel · Des Moines
from €59/night ★ 3
Motel 6-Des Moines, IA - North
hotel · Des Moines
from €60/night ★ 3
AmericInn by Wyndham Des Moines Airport
hotel · Des Moines
from €65/night ★ 3
Good to know Time difference Same time zone
Time in the air 3h 16m
About Des Moines
Des Moines, capital of Iowa, is in the western region of the American Midwest. Des Moines is the largest city in Iowa and the annual site of the Iowa State Fair and numerous cultural festivals during warm weather months. History enthusiasts will find 110 historic sites in and around the city as part of the Silos and Smokestacks National Heritage Area.
Read the full Des Moines guide
Guide content from Wikivoyage contributors (CC BY-SA).
Popular from San Antonio Cheapest destinations travellers searched recently — refreshed daily.
Flight prices are real fares travellers found in the last 48 hours, refreshed daily — the booking site confirms the final price. Train, bus and ferry fares are shown on the operators' booking sites. Weather data by Open-Meteo ; exchange rates: ECB reference. Data updated 2026-08-28. Some links earn Stayonomy a commission at no cost to you.