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4h 45mduration
€387–534recent fares
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Cheapest cached fares Santo Domingo → Guayaquil; typically 2 stops (e.g. Y2). · Based on 3 fares found by travellers in the last 48h
Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.
Best value: Sep — fares from €387 and ~32°C daytime.
Flights from Santo Domingo to Guayaquil start around €387 (typically 2 stops). Range seen recently: €387–534, based on 3 fares found by travellers.
In Aug, Guayaquil typically sees ~32°C daytime highs and 0 rainy days.
3★+ hotels from €23/night (24 hotels sampled, ~3 weeks out).
Top-rated tours and tickets from €102 — book ahead for the popular ones.
Tours and tickets provided by Viator (a Tripadvisor company). Some links earn Stayonomy a commission.
Guayaquil is the largest city in Ecuador. This article also covers Durán, which is a UNESCO Creative City on the other side of the river.
Guide content from Wikivoyage contributors (CC BY-SA).
Cheapest destinations travellers searched recently — refreshed daily.
Flight prices are real fares travellers found in the last 48 hours, refreshed daily — the booking site confirms the final price. Train, bus and ferry fares are shown on the operators' booking sites. Weather data by Open-Meteo; exchange rates: ECB reference. Data updated 2026-08-02. Some links earn Stayonomy a commission at no cost to you.