Santo Domingo to Medellin

1 ways to travelfastest 4h 35mfly from €411
Photo: Joel Duncan / Unsplash

How the cheapest fare moved

Sep 4: €643 €643 Sep 1 Sep 4 low €411 · high €643

Departure-day prices · September 2026 Santo Domingo → Medellin

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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.

Return-day prices · September 2026 Medellin → Santo Domingo

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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.

Best time to visit Medellin — climate

Jan: ~27°C daytime, 14 rainy days 27° JanFeb: ~26°C daytime, 27 rainy days 26° FebMar: ~27°C daytime, 26 rainy days 27° MarApr: ~27°C daytime, 26 rainy days 27° AprMay: ~27°C daytime, 23 rainy days 27° MayJun: ~27°C daytime, 24 rainy days 27° JunJul: ~28°C daytime, 14 rainy days 28° JulAug: ~27°C daytime, 20 rainy days 27° AugSep: ~27°C daytime, 21 rainy days 27° SepOct: ~26°C daytime, 27 rainy days 26° OctNov: ~27°C daytime, 26 rainy days 27° NovDec: ~26°C daytime, 19 rainy days 26° Dec

Flights from Santo Domingo to Medellin start around €411 (typically 2 stops). Range seen recently: €411–643, based on 3 fares found by travellers.

Fly (from €411)
4h 35mduration
€411–643recent fares
Book
Cheapest cached fares Santo Domingo → Medellin; typically 2 stops (e.g. Y2). · Based on 3 fares found by travellers in the last 48h

Cheapest round trips to Medellin

Fares found by travellers in the last 48 hours — refreshed daily.

Sep 18 – Sep 21 Sunrise Airways · 2 stops · 6h 10m €1927 Book

Weather in Medellin

Mon 🌦️ 27° 15° 💧47%
Tue 🌦️ 29° 17° 💧31%
Wed 🌦️ 30° 17° 💧71%
Thu 🌦️ 30° 17° 💧67%
Fri 🌦️ 29° 17° 💧76%
Sat 🌦️ 30° 17° 💧70%
Sun 🌦️ 30° 17° 💧70%

In Sep, Medellin typically sees ~27°C daytime highs and 21 rainy days.

Where to stay in Medellin

3★+ hotels from €34/night (40 hotels sampled, ~3 weeks out).

ibis budget Medellín Itagüí Metro hotel · Medellin
from €34/night★ 3
Hotel Egina Medellin hotel · Medellin
from €43/night★ 4
Hashtag 98 Hotel By Jalo hotel · Medellin
from €49/night★ 4

Good to know

Time difference-1h
Time in the air6h 10m

About Medellin

Medellín is the second largest city in Colombia. It has 2.62 million residents (2024) and is the capital of the department of Antioquia. It's set in a valley running south to north and just a one-hour flight from Bogotá. For international travelers, Medellín is perhaps most famous for the Antioquia Museum, with its extensive collection of Botero paintings inside and Botero sculptures outside on its main plaza. The city is also known for its perfect climate with its nickname "city of the eternal spring".

Read the full Medellin guide

Guide content from Wikivoyage contributors (CC BY-SA).

Round out the trip

Popular from Santo Domingo

Cheapest destinations travellers searched recently — refreshed daily.

Flight prices are real fares travellers found in the last 48 hours, refreshed daily — the booking site confirms the final price. Train, bus and ferry fares are shown on the operators' booking sites. Weather data by Open-Meteo; exchange rates: ECB reference. Data updated 2026-09-07. Some links earn Stayonomy a commission at no cost to you.