How the cheapest fare moved
Oct 24: €252 €252
Oct 18
Oct 24
low €250 · high €370
Departure-day prices · October 2026 Santo Domingo → Panama City
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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.
Return-day prices · October 2026 Panama City → Santo Domingo
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26 €403 27
28 €473 29
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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.
Best time to visit Panama City — climate Jan: ~31°C daytime, 20 rainy days
31°
Jan Feb: ~32°C daytime, 17 rainy days
32°
Feb Mar: ~33°C daytime, 13 rainy days
33°
Mar Apr: ~32°C daytime, 23 rainy days
32°
Apr May: ~30°C daytime, 31 rainy days
30°
May Jun: ~29°C daytime, 30 rainy days
29°
Jun Jul: ~31°C daytime, 30 rainy days
31°
Jul Aug: ~30°C daytime, 29 rainy days
30°
Aug Sep: ~30°C daytime, 29 rainy days
30°
Sep Oct: ~29°C daytime, 30 rainy days
29°
Oct Nov: ~29°C daytime, 28 rainy days
29°
Nov Dec: ~30°C daytime, 21 rainy days
30°
Dec Best value: Nov — fares from €250 and ~29°C daytime.
Flights from Santo Domingo to Panama City start around €250 (direct flights available). Range seen recently: €250–303, based on 5 fares found by travellers.
Fly (from €250)
2h 33m duration
€250–303 recent fares
Book
Cheapest cached fares Santo Domingo → Panama City; direct flights available (e.g. CM). · Based on 5 fares found by travellers in the last 48h
Cheapest round trips to Panama City Fares found by travellers in the last 48 hours — refreshed daily.
Feb 12 – Feb 15
avianca airlines · 1 stop · 4h 25m
€450
Book
Mar 19 – Mar 23
Copa Airlines · Direct · 2h 35m
€462
Book
Mar 19 – Mar 20
Copa Airlines · Direct · 2h 35m
€481
Book
Dec 28 – Jan 11
Copa Airlines · Direct · 2h 35m
€496
Book
Feb 26 – Mar 14
Copa Airlines · Direct · 2h 36m
€512
Book
Dec 7 – Dec 22
Copa Airlines · Direct · 2h 37m
€578
Book
Dec 7 – Dec 23
Copa Airlines · Direct · 2h 35m
€578
Book
Aug 10 – Aug 13
avianca airlines · 1 stop · 4h 20m
€622
Book
Weather in Panama City
Fri
🌧️
32°
25°
💧63%
Sat
🌧️
31°
24°
💧100%
Sun
⛈️
29°
24°
💧99%
Mon
⛈️
29°
24°
💧93%
Tue
🌦️
31°
25°
💧86%
Wed
🌧️
30°
24°
💧86%
Thu
🌦️
32°
24°
💧82%
In Oct, Panama City typically sees ~29°C daytime highs and 30 rainy days.
Where to stay in Panama City 3★+ hotels from €44/night (37 hotels sampled, ~3 weeks out).
Hotel Principe
hotel · Panama City
from €44/night ★ 4
Radisson Hotel Panama Canal
hotel · Panama City
from €58/night ★ 5
Riande Urban Hotel
hotel · Panama City
from €60/night ★ 4
Good to know Time difference -1h
Time in the air 2h 35m
Things to do in Panama City Top-rated tours and tickets from €36 — book ahead for the popular ones.
Tours and tickets provided by Viator (a Tripadvisor company). Some links earn Stayonomy a commission.
About Panama City
Capital of Panama and the most populous city in the country, it is located on the Pacific coast, near the entrance of the Panama Canal.
Read the full Panama City guide
Guide content from Wikivoyage contributors (CC BY-SA).
Popular from Santo Domingo Cheapest destinations travellers searched recently — refreshed daily.
Flight prices are real fares travellers found in the last 48 hours, refreshed daily — the booking site confirms the final price. Train, bus and ferry fares are shown on the operators' booking sites. Weather data by Open-Meteo ; exchange rates: ECB reference. Data updated 2026-10-24. Some links earn Stayonomy a commission at no cost to you.
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