Medellin to Santiago

1 ways to travelfastest 6h 10mfly from €188
Photo: Chalo Gallardo / Unsplash

How the cheapest fare moved

Oct 10: €217 €217 Oct 3 Oct 10 low €188 · high €217

Departure-day prices · October 2026 Medellin → Santiago

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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.

Return-day prices · October 2026 Santiago → Medellin

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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.

Best time to visit Santiago — climate

Jan: ~31°C daytime, 0 rainy days 31° JanFeb: ~31°C daytime, 0 rainy days 31° FebMar: ~28°C daytime, 2 rainy days 28° MarApr: ~23°C daytime, 0 rainy days 23° AprMay: ~19°C daytime, 6 rainy days 19° MayJun: ~15°C daytime, 3 rainy days 15° JunJul: ~16°C daytime, 1 rainy days 16° JulAug: ~16°C daytime, 9 rainy days 16° AugSep: ~20°C daytime, 3 rainy days 20° SepOct: ~24°C daytime, 3 rainy days 24° OctNov: ~26°C daytime, 2 rainy days 26° NovDec: ~29°C daytime, 2 rainy days 29° Dec

Flights from Medellin to Santiago start around €188 (direct flights available). Range seen recently: €188–406, based on 5 fares found by travellers.

Fly (from €188)
6h 10mduration
€188–406recent fares
Book
Cheapest cached fares Medellin → Santiago; direct flights available (e.g. JA). · Based on 5 fares found by travellers in the last 48h

Cheapest round trips to Santiago

Fares found by travellers in the last 48 hours — refreshed daily.

Apr 2 – Apr 11 JetSmart · Direct · 6h 10m €320 Book
Apr 2 – Apr 10 JetSmart · Direct · 6h 10m €336 Book
Apr 2 – Apr 9 JetSmart · Direct · 6h 10m €337 Book
Dec 26 – Jan 4 JetSmart · Direct · 6h 12m €339 Book
Apr 4 – Apr 11 JetSmart · Direct · 6h 10m €357 Book
Dec 27 – Jan 4 JetSmart · Direct · 6h 12m €366 Book
Apr 4 – Apr 10 JetSmart · Direct · 6h 10m €367 Book
Apr 3 – Apr 11 JetSmart · Direct · 6h 10m €370 Book

Weather in Santiago

Fri 🌦️ 18° 8° 💧98%
Sat 🌦️ 21° 9° 💧31%
Sun 🌦️ 19° 12° 💧76%
Mon 🌦️ 16° 10° 💧100%
Tue 🌦️ 15° 9° 💧100%
Wed 🌦️ 17° 8° 💧90%
Thu 🌦️ 19° 7° 💧80%

In Oct, Santiago typically sees ~24°C daytime highs and 2 rainy days.

Where to stay in Santiago

3★+ hotels from €49/night (38 hotels sampled, ~3 weeks out).

Hotel Fundador hotel · Santiago
from €49/night★ 4
hUB Providencia hotel · Santiago
from €50/night★ 4
Hotel Panamericano hotel · Santiago
from €52/night★ 3

Good to know

Time difference+2h
Time in the air6h 10m

Things to do in Santiago

Top-rated tours and tickets from €25 — book ahead for the popular ones.

Tours and tickets provided by Viator (a Tripadvisor company). Some links earn Stayonomy a commission.

About Santiago

Santiago is the capital and economic center of Chile. With its many museums, events, theaters, restaurants, bars and other entertainment and cultural opportunities, it is also the cultural center of the country. For visitors it's both the gateway to the country and a destination in its own right with an eclectic architecture, a vibrant culinary and cultural scene, surrounded by the mighty Andes welcoming skiers, trekkers and friends of wine.

Read the full Santiago guide

Guide content from Wikivoyage contributors (CC BY-SA).

Round out the trip

Popular from Medellin

Cheapest destinations travellers searched recently — refreshed daily.

Flight prices are real fares travellers found in the last 48 hours, refreshed daily — the booking site confirms the final price. Train, bus and ferry fares are shown on the operators' booking sites. Weather data by Open-Meteo; exchange rates: ECB reference. Data updated 2026-10-10. Some links earn Stayonomy a commission at no cost to you.