Santo Domingo to Medellin

1 ways to travelfastest 2h 30mfly from €122
Photo: Joel Duncan / Unsplash

Departure-day prices · September 2026 Santo Domingo → Medellin

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Return-day prices · September 2026 Medellin → Santo Domingo

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Cheapest days highlighted · darker = pricier · past days greyed out · cached one-way fares.

Best time to visit Medellin — climate

Jan: ~27°C daytime, 14 rainy days 27° JanFeb: ~26°C daytime, 27 rainy days 26° FebMar: ~27°C daytime, 26 rainy days 27° MarApr: ~27°C daytime, 26 rainy days 27° AprMay: ~27°C daytime, 23 rainy days 27° MayJun: ~27°C daytime, 24 rainy days 27° JunJul: ~28°C daytime, 14 rainy days 28° JulAug: ~27°C daytime, 20 rainy days 27° AugSep: ~27°C daytime, 21 rainy days 27° SepOct: ~26°C daytime, 27 rainy days 26° OctNov: ~27°C daytime, 26 rainy days 27° NovDec: ~26°C daytime, 19 rainy days 26° Dec

Best value: Feb — fares from €122 and ~26°C daytime.

Flights from Santo Domingo to Medellin start around €122 (direct flights available). Range seen recently: €122–309, based on 2 fares found by travellers.

Fly (from €122)
2h 30mduration
€122–309recent fares
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Cheapest cached fares Santo Domingo → Medellin; direct flights available (e.g. P5). · Based on 2 fares found by travellers in the last 48h

Cheapest round trips to Medellin

Fares found by travellers in the last 48 hours — refreshed daily.

Oct 24 – Oct 28 Arajet · Direct · 2h 35m €240 Book
Jul 31 – Aug 7 Arajet · Direct · 2h 35m €276 Book
Nov 6 – Nov 9 avianca airlines · 1 stop · 3h 35m €310 Book
Mar 21 – Mar 28 Arajet · Direct · 2h 30m €380 Book
Jul 25 – Jul 27 Wingo · Direct · 2h 28m €479 Book

Weather in Medellin

Wed ⛈️ 28° 17° 💧86%
Thu 🌧️ 26° 17° 💧98%
Fri 🌦️ 29° 17° 💧68%
Sat 🌦️ 29° 16° 💧63%
Sun 🌦️ 28° 17° 💧55%
Mon 🌧️ 25° 17° 💧86%
Tue 🌦️ 28° 17° 💧54%

In Sep, Medellin typically sees ~27°C daytime highs and 21 rainy days.

Where to stay in Medellin

3★+ hotels from €33/night (36 hotels sampled, ~3 weeks out).

ibis budget Medellín Itagüí Metro hotel · Medellin
from €33/night★ 3
Tequendama Hotel Medellín - Estadio hotel · Medellin
from €49/night★ 4
Hotel Egina Medellin hotel · Medellin
from €53/night★ 4

Good to know

Time difference-1h
Time in the air2h 28m

About Medellin

Medellín is the second largest city in Colombia. It has 2.62 million residents (2024) and is the capital of the department of Antioquia. It's set in a valley running south to north and just a one-hour flight from Bogotá. For international travelers, Medellín is perhaps most famous for the Antioquia Museum, with its extensive collection of Botero paintings inside and Botero sculptures outside on its main plaza. The city is also known for its perfect climate with its nickname "city of the eternal spring".

Read the full Medellin guide

Guide content from Wikivoyage contributors (CC BY-SA).

Round out the trip

Popular from Santo Domingo

Cheapest destinations travellers searched recently — refreshed daily.

Flight prices are real fares travellers found in the last 48 hours, refreshed daily — the booking site confirms the final price. Train, bus and ferry fares are shown on the operators' booking sites. Weather data by Open-Meteo; exchange rates: ECB reference. Data updated 2026-07-22. Some links earn Stayonomy a commission at no cost to you.